Eukaryotes differ from prokaryotes in the mechanism of DNA replication due to
A)Same enzymes are used for the synthesis of lagging and leading strands in prokaryote and eukaryote
B)Discontinuous rather than semi discontinuous replication
C)Use of DNA primers rather than RNA primers
D)Unidirectional rather than bidirectional replication
Answer
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Hint: In nature, replication of DNA is semi-conservative. The double-stranded helical base of nucleotides is present in the DNA. Uncoiling of the double-strand at the beginning of the replication process takes place that separates into 2 single strands and then this strand is copied, results and replicated and forms the new daughter strands of DNA from the parent helix.
Complete answer:
Eukaryotes differ from prokaryotes in the mechanism of DNA replication. Differences are -
Additional information
When the double helix of DNA unwinds, DNA replication on one of the two strands (3' to 5' stand) can easily proceed continuously in a 5' to 3' direction. This is the leading strand. On the other strand (5'-3') if the synthesis has to take place in a 5' to 3' direction, it has to be synthesized in a direction opposite to that on the leading strand. This strand is the lagging strand and on this strand, synthesis takes place in segments discontinuously and these segments are then fused to create an intact lagging strand. This behavior where the leading strand is synthesized continuously and the lagging strand is synthesized discontinuously is called semi-discontinuous replication.
Discontinuous replication - In this short segments are joined together when the synthesis of new strands of replicating DNA molecules takes place. Only the lagging strand is synthesized in this way and the leading strand is synthesized by the continuous addition of nucleotides to the growing end.
So, the correct answer is, “Discontinuous rather than semi discontinuous replication”.
Note:
-Short DNA fragments known as Okazaki fragments are produced by the discontinuous replication which is complementary to the template strand.
-Semi discontinuous model of DNA replication shows that on the leading strand DNA synthesis is continuous whereas on the lagging strand DNA synthesis is discontinuous.
Complete answer:
Eukaryotes differ from prokaryotes in the mechanism of DNA replication. Differences are -
| Eukaryotes | Prokaryotes |
| Eukaryotes have multiple points of origin. | One point of origin is present in prokaryotic DNA |
| In eukaryotes, DNA replication is discontinuous. -In the 5' to 3' direction on the leading strand, DNA is synthesized by DNA polymerase. | In prokaryotes, the DNA replication is semi discontinuous |
| -When the DNA polymerase works in the opposite direction on the lagging strand it synthesizes discontinuous short DNA segments known as Okazaki in 3'-5' direction. | -Without any need for discontinuous replication, both the strands are copied in 5' to 3' directions in adenovirus. |
Additional information
When the double helix of DNA unwinds, DNA replication on one of the two strands (3' to 5' stand) can easily proceed continuously in a 5' to 3' direction. This is the leading strand. On the other strand (5'-3') if the synthesis has to take place in a 5' to 3' direction, it has to be synthesized in a direction opposite to that on the leading strand. This strand is the lagging strand and on this strand, synthesis takes place in segments discontinuously and these segments are then fused to create an intact lagging strand. This behavior where the leading strand is synthesized continuously and the lagging strand is synthesized discontinuously is called semi-discontinuous replication.
Discontinuous replication - In this short segments are joined together when the synthesis of new strands of replicating DNA molecules takes place. Only the lagging strand is synthesized in this way and the leading strand is synthesized by the continuous addition of nucleotides to the growing end.
So, the correct answer is, “Discontinuous rather than semi discontinuous replication”.
Note:
-Short DNA fragments known as Okazaki fragments are produced by the discontinuous replication which is complementary to the template strand.
-Semi discontinuous model of DNA replication shows that on the leading strand DNA synthesis is continuous whereas on the lagging strand DNA synthesis is discontinuous.
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